Never use Brinzox Ophthalmic Suspension if the seal is broken before you use it for the first time. Wash your hands before using it and shake the bottle well before each use. If you wear contact lenses, make sure you remove them before instilling them and wait for at least 15 minutes before putting them back. Do not stop using this medicine without asking your doctor. Otherwise, the pressure in your eye will not be controlled and this could damage your sight.